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How long does Cialis last for you?
One of the most effective medications for treatment of erectile dysfunction (ED) is Cialis. This product enhances blood circulation in the pelvis and provides intense blood flow to the penis, causing an erection.
Cialis differs from other drugs for erectile dysfunction treatment by longer action. If you wonder how long action of Cialis can last, then the following information will be helpful.
Cialis acts basing on temporary inhibition of the phosphodiesterase type 5 enzyme, leading to vasodilatation and relaxation of smooth muscles of the corpora cavernosa. Because of this effect, the penis is filled with blood and an erection is achieved.
Cialis pills are quickly absorbed in the gastrointestinal tract, and the average maximum concentration of Cialis in the blood is reached in about 2 hours after intake. Cialis half-life is about 17 hours, and the drug effect may last for 36 hours.
It should be noted, unlike other drugs for ED treatment, Cialis starts acting within 30 minutes after ingestion, and can last more than one day. Neither alcohol nor fatty foods affect Cialis action.
Cialis is easy to use and can be taken only when necessary. The drug has no effect on sexual partners life and does not require men to adapt to its action period.
However, it should be noted that the effectiveness of erectile dysfunction treatment can be affected by medications used with Cialis. Some of them may reduce Cialis efficacy, while others increase the drug effect.
The effect and duration of Cialis action can be increased by Itraconazole, Ketoconazole, and Erythromycin. If men use these medications with Cialis, therapeutic effects of Cialis may last longer than usual. Inhibitors of CYP3A4 enzyme (for example, Rifampin) may reduce Cialis duration and effectiveness at the average by more than 80%.
In most cases, the duration of Cialis effect depends on the used dose. The higher the dose of Cialis, the longer the clinical effect provided.
As a rule, in elderly patients (above 65 years) Cialis action lasts not so long as in young adults. It can be explained by the fact that older men may not respond to Cialis like young men’s organism. Many older men have serious diseases that can affect the effectiveness of ED therapy.